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Educational purposes only — not medical advice. Consult your gastroenterologist before changing any regimen. Full disclaimer We may earn a commission on recommended products, at no extra cost to you. Disclosure

Category 01

Natural supplements & botanicals for Crohn’s support

Time-honoured herbs and nutrients that researchers have studied in people with inflammatory bowel disease — from turmeric and wormwood to Boswellia and omega-3s. How they work, what the studies found, and how to choose a quality product.

Curcumin (Turmeric)

Mixed results

Turmeric extract · Curcuma longa · Theracurmin

Turmeric’s golden compound supports a healthy inflammation response and is the most-researched botanical in inflammatory bowel disease.

3 studies summarised
Read the evidence

Wormwood (Artemisia absinthium)

Early clinical

Artemisia absinthium · Absinthe herb · Wermut

A traditional digestive bitter that showed striking results in two Crohn’s studies, including measurable reductions in TNF-α.

2 studies summarised
Read the evidence

Boswellia serrata

Mixed results

Indian frankincense · Salai guggal · H15

Indian frankincense resin that targets a distinctive inflammatory pathway and performed on par with mesalazine in an active-Crohn’s trial.

2 studies summarised
Read the evidence

Omega-3 Fatty Acids (EPA/DHA)

Mixed results

Fish oil · EPA · DHA

Essential fatty acids that feed your body’s inflammation-resolving pathways. Promising early Crohn’s results; larger trials were mixed.

3 studies summarised
Read the evidence

Probiotics (VSL#3, E. coli Nissle, S. boulardii)

Mixed results

VSL#3 · Escherichia coli Nissle 1917 · Saccharomyces boulardii

Beneficial bacteria that help rebalance the gut microbiome. Standout results in pouchitis and ulcerative colitis; Crohn’s results are still emerging.

3 studies summarised
Read the evidence

CBD-Rich Cannabis

Mixed results

Cannabidiol · CBD oil · Medical cannabis

CBD-rich cannabis significantly improved symptoms and quality of life in randomised Crohn’s trials.

2 studies summarised
Read the evidence

Andrographis paniculata (HMPL-004)

Clinically studied

HMPL-004 · Andrographolide · Kalmegh

The “king of bitters” — the only botanical taken into a Phase III IBD programme, with results comparable to mesalazine in ulcerative colitis.

2 studies summarised
Read the evidence

Phase 2 — in development

Where traditional research stops, our community begins

Natural compounds can’t be patented, so they rarely get the multi-million-dollar trials that drugs receive. That leaves people with Crohn’s without answers to the questions that matter most: what actually helps, at what dose, and for whom? Our Community Symptom Tracker will crowdsource those answers from real people living with Crohn’s, and our upcoming wellness store will make it easy to find quality, third-party-tested products.

  • Log your symptoms, supplements and doses in a private daily tracker
  • See what’s working for people with the same disease location and medications
  • Contribute to the largest real-world dataset on natural Crohn’s support
  • Shop curated, third-party-tested protocols from our upcoming store

Be one of the first to join

Early access is opening soon. Bookmark this page and check back — we’ll announce sign-ups here first.

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